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Gq/11 interacts with PLC, which may split a fat-like molecule, phosphatidylinositol 4,5-bisphosphate (PIP2), into two messaging molecules: IP3 (Inositol trisphosphate) and DAG (Diacylglycerol)

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The 14-3-3 protein binds to C-Abl, pushing it to localize in the cytoplasm and inhibiting lowering the production of caspase-8 and caspase-9, blocking the intrinsic apoptotic pathway, and the caspase promoter (Raina et al., 2005