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Originally, Gurneys operation was located in eastern Iowa, but he eventually moved to Dixon County in Nebraska, which sits along the Missouri River, not far from Vermillion, South Dakota

This figure depicts the three components of our trend analysis: (1) development of a population-based intestinal-type NCGA microsimulation model, which explicitly incorporates birth cohort-specific risk factor trends, background mortality rates, and population size, and identifies natural history progression rates via model calibration to US epidemiologic data