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On day 4, 48 h post-transfection, cells were treated with the ferroptosis-inducing compounds erastin, RSL3, or FINO2 in the presence or absence of Ferrostatin-1 (Fer-1) as indicated

And then the rest of the movie is about getting out

This results in activated T cells & B cells that produce an anti-citrulline inflammatory response that affects the joints, resulting in swelling and degradation of both cartilage and bone (Schur & Firestein, 2012) as illustrated in Figures 3, 4 & 5

Zhao R, Zhang W, Ma C, Zhao Y, Xiong R, Wang H et al (2021) Immunomodulatory Function of Vitamin D and Its Role in Autoimmune Thyroid Disease