Santoro MM
Potential risks Serious risks and adverse events include: Allergic reaction to the medications or dye used in the injection Shoulder infection Depigmentation of the skin around the injection site (a whitening of the skin) Local fat atrophy around the injection site (thinning of the skin) Rupture of a tendon located in the path of the injection Nerve damage near the shoulder joint Bleeding at the injection site In addition to the above, corticosteroid injections increase the risk of: High blood pressure High blood sugar Decreased immune function Decrease in bone mineral density Bone infection (osteonecrosis) Reproductive hormone imbalance Metabolic changes (eg, increased appetite, weight gain, and fluid retention) These risks are typically associated with higher doses of corticosteroids, multiple injections, and for people with underlying medical conditions such as diabetes and heart problems
Product Attributes Scientific References GLP-2T Trzptd once weekly for the treatment of obesity Human RCT Trzptd : a systematic update Review Trzptd versus smglutd once weekly in patients with type 2 diabetes Human RCT Efficacy and safety of once-weekly trzptd versus once-daily insulin degludec as add-on to metformin in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial Human RCT Dual GIP and GLP-1 receptor agonist Trzptd improves beta-cell function and insulin sensitivity in type 2 diabetes Human observational Effects of novel dual GIP and GLP-1 receptor agonist trzptd on biomarkers of inflammation and cardiovascular risk in patients with type 2 diabetes Human RCT LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: from discovery to clinical proof of concept Animal A long-term safety study of trzptd (LY3298176) in participants with type 2 diabetes Human RCT Effect of trzptd versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial Human RCT Once-weekly smglutd in adolescents with obesity (comparative to trzptd context) Human RCT 5-Amino-1MQ Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice Animal Roles of nicotinamide N-methyltransferase in obesity and type 2 diabetes mellitus Review What is 5-Amino-1MQ
A snapshot on the on-label and off-label use of the interleukin-1 inhibitors in Italy among rheumatologists and pediatric rheumatologists: a nationwide multi-center retrospective observational study
