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Parameters to monitor Serum electrolytes (especially creatinine and potassium) Symptoms of angioedema BP Symptoms of hypotension CBC (especially with captopril and enalapril) for neutropenia, which is more common in patients with preexisting renal impairment Cough Urinary proteins Direct Renin Inhibitors See Table 12-16 for a list of direct renin inhibitors, their usual dosage range, and adverse effects associated with these medications

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Anemia: Especially B12-deficiency anemia can improve with Neurobion injectable therapy

This approach isolates any adverse effects to the new agent rather than conflating them with tirzepatide's known tolerability profile