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Gastroenterology 117 , 327335 (1999)

Precision microbial intervention improves social behavior but not autism severity: A pilot double-blind randomized placebo-controlled trial

Community-reported (anecdotal): headache, brain fog or mental fatigue, irritability, anxiety, nausea or other GI upset, appetite and sleep changes, blood-pressure changes, and skin reactions with transdermal-DMSO use

As they fluctuate and decline, several issues can arise: Increased hair thinning : Estrogen hair loss connection with perimenopause leads to hair follicles spending less time in the growth phase (anagen) and more time in the shedding phase (telogen), resulting in overall thinning