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Targeting RB1 may disrupt the control of the cell cycle in MDSCs, leading to reduced proliferation and accumulation within the TME, thereby weakening their capacity to inhibit anti-tumor immune responses by lymphoid and myeloid cells [31]

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Numerous studies have demonstrated that HO-1 has a significant effect on diabetic complications, with induction of HO-1 protein expression enhancing antioxidant defense and reducing inflammatory factors (Table 2)

Male patients with thicker skin and heavier facial tissue who require deep-reaching structural lifting