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Parakh et al., 2020), thus linking redox dysregulation to protein misfolding and sporadic ALS

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The most often and potent ones attracted are the insulin receptor substrates 1/2 (IRS1/2)although there are 6 found to date- (not to forget that Shc proteins, p60dok, Cbl, APS, and Gab-1 are also recruited to activated IRs)

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(2) 2023 TCM Evidence-Based Capacity Enhancement Project

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