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This widespread misunderstanding is a major barrier, preventing smokers from exploring a much safer alternative

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A traumatic home invasion in 1981 later affected her already compromised health, adding personal trauma to physical challenges

23 Coverage often included anecdotes about having tried nicotine replacement therapies (NRTs), failing to quit, and then trying the e-cigarette (such as the celebrity endorsement by actress Katherine Heigl on the US David Letterman television program 21 ), implying that e-cigarettes are a more effective form of NRT