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Retatrutide additionally shows a dose-dependent increase in heart rate, attributed to its glucagon-receptor activity, and indirect network meta-analyses flag the highest adverse-event burden among the modern agents for the most potent drugs

The production of BSP libraries, sequencing, and bioinformatics analysis were performed as described in 18 with minor modifications

Peptides, by comparison, remain experimental and should not be considered equivalent to licensed treatments

The peptide has an extremely short half-life, as little as 30 minutes, which means that unlike other banned substances, the odds of detecting this substance in testing are much lower