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Probiotics exert their beneficial effects through various mechanisms, such as competitive inhibition of pathogenic microorganisms, modulation of the gut microbiota, and enhancement of immune functions

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In mammals, ferroptosis has been implicated in diverse pathologies, including neurodegenerative diseases, stroke, traumatic brain injury and kidney degeneration, as well as in carcinogenesis, where it may exert a tumor-suppressor function

Additionally, the expression of genes related to the immunosuppressive functions of Treg cells (such as IL-10, CTLA-4, and TGF-) was downregulated, which weakened their ability to inhibit CD8 + T cell activity