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The through line of history is that people will try to sell anything with all sorts of fantastical claims, Joshua Sharfstein, a health-policy professor at Johns Hopkins and a former principal deputy commissioner of the F.D.A., told me

However, other supplementations, such as vitamin E, C, and ferrous sulfate, did not offer a significant reduction in the depression score in this study due to many factors, such as the short trial duration, limited sample size in each group, low effective doses, and inadequate measurement at the start and end of the trial

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