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This difference was likely attributable to the insufficient inhibition of excessive GJ proteins in hepsin / mice in response to the lower 2APB dose of 1 mg/kg, lending further support to the hypothesis that hepsin may help reduce APAP toxicity by regulating the expression of hepatic GJ proteins

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Compared to larger studies, it is difficult to gain further mechanistic insight in our study, including individual variability of fasting response

(CNN) A little-known advisory group to the US Food and Drug Administration will meet this week to mull over whether to ease restrictions on certain peptides