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Prakhar Agrawal, an Analyst at Cantor Fitzgerald, wrote in February 2025 that a lot of fine-tuning still needs to be done on dosing, noting that the low-dose group appeared to plateau at around 52 weeks while the high-dose group had not

Treatment reduces circulating markers of metabolic dysfunction and inflammation, creating a more favorable metabolic environment that supports insulin sensitivity and glucose regulation

This distinction between the factors controlling the time to reach steady state and the factors controlling the level of steady state is clinically important

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