is too much glutathione bad for you deficiency and heart failure: a systematic review of human and animal evidence What Happens When You Stop

Otherwise, they're trying to essentially knock down the quote, unquote, positive outcome

Both NAD and glutathione forms are used as cofactors and posttranslational modifications in proteins involved in biosynthesis reactions

Taken together, these observations suggest that except in vitamin B 12 deficiency (which only responds to cyanocobalamin treatment because of the inactivation of methionine synthase), folate treatment should be the most adequate therapy to reverse hyperhomocysteinemia detected both under basal conditions and after an oral methionine load

In hypothyroidism (including in autoimmune hypothyroidism), slower gut transit time is common, which can favor microbial overgrowth, including candida or opportunistic yeasts and bacteria