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However, other studies have challenged the presence or functional relevance of mLOC, arguing instead that lactate is likely to first be converted to pyruvate in the cytosol before being imported into mitochondria via the mitochondrial pyruvate carrier (MPC) [32]

and conduct a deeper analysis of the molecular pathways that mediate the effects of Rg1 to fully understand its role in neurodegenerative disease treatment

Cohort studies published in Environmental Health Perspectives report significantly elevated PD incidence among populations with high PM2.5 exposure [93]