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In conclusion, we found that ALC significantly reduced SREBP2 and HMGCR expression, leading to decreased de novo cholesterol synthesis, lower serum cholesterol levels in HCD-fed mice, and attenuated atherosclerotic progression

Hence, each docked complex, i.e., mh-Tyr-flavonoids and mh-Tyr-ABR inhibitor, were simulated under OPLS-2005 force field with explicit (TIP4P) water solvent for 100 ns interval

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