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Topoisomerase IIbeta mediated DNA double-strand breaks: implications in doxorubicin cardiotoxicity and prevention by dexrazoxane

Research indicates that low maternal B12 status is associated with a higher risk of adverse outcomes, including neural tube defects, preterm birth, low birth weight and potential impacts on cognitive development, although evidence of direct causation remains limited

Oxidative stress can damage lipids, proteins, and DNA, which can cause cellular dysfunction and tissue damage ( A crucial part of physiological balance is the complicated relationship between antioxidants in the diet and oxidative stress-induced adrenal hormone imbalance ( The primary objective of this review is to elucidate the mechanisms by which adrenal hormone imbalance induces oxidative stress and investigate the potential contributions of nutritional antioxidants in mitigating such imbalances

2) Why physicians prescribe compounded drugs Patient-specific formulations: Alternative strengths, routes (e.g., rectal suppositories for GI indications), or dosage forms