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Trichotomization: Q1vsQ4) reveals that a high expression of four genes (TDO2, IDO1, IDO2, and Slc7a11) involved in kynurenine synthesis, from tryptophan, and transport is associated with a worse prognosis [256]

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[123] [124] Toxic exposure [edit] Multiple studies have attempted to study the relationship between toxic exposure and autism, despite limitations related to the measurement of toxic exposure the methods for which were often indirect and cross-sectional