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Lagisetty KH, Atluri P, Boden NJ, Donington JS, Ikonomidis JS, Rice DC , Sengewald DE, Tseng EE, Weyant MJ, Savage Yohe C, Yang SC

chelation of the copper site by the thiol group, interference with the cellular transfer of tyrosinase to premelanosomes, which is the site of melanin synthesis and indirect inhibition of tyrosinase via its antioxidant effect as the free radical scavenging effect of it blocks the induction of tyrosinase activity caused by peroxides

Before committing to either, knowing your baseline NAD+ level tells you whether NAD+ deficiency is part of what youre dealing with, which changes how any protocol should be sequenced