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Beide peptiden worden individueel geanalyseerd op zuiverheid via reversed-phase HPLC en op moleculaire identiteit via LC-MS/MS voordat ze worden gecombineerd

These pathogenic processes ultimately result in massive -cell loss and absolute insulin deficiency, thereby inducing dysregulation of glucose homeostasis (164)

Critical limitations identified in the systematic review include predominant use of small rodent models (primarily rats), short follow-up periods relative to human healing timelines, variable dosing regimens complicating dose-response assessment, and lack of standardized outcome measures across studies

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