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On page 244 of that novel, the character Chris Haines says, "I knew you didnt call me in here to blow smoke up my ass." While Snopes cannot verify if this is truly the first published instance of the phrase, other research methods support a roughly 1960s origin for the phrase as well

After a Mans Heart would be an example of one appearing on the back cover of the New York State Journal of Medicine in 1937, and the irony of what smoking does to the heart would not be evident until about 20 years later

One simple action can interrupt the smoking habit loop

Before fermentation, the tobacco must be re-moistened to make it flexible and reactive