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They may be seen one year but whether they will be seen the next year cannot be predicted

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Some scholars argue that for individuals already addicted to smoking, switching to vaping could be a permissible form of harm reduction, provided the ultimate goal is to cease nicotine use entirely

Pre-treatment with allopurinol (a xanthine oxidase inhibitor) or dimethyl sulfoxide (DMSO) (a hydroxyl free radical scavenger) can block the apoptotic activity induced by smoking, and does not affect the p53 level of the mucosa (26), suggesting that the apoptosis induced by cigarette smoking is mediated through reactive oxygen species (ROS) and occurs independently of the p53 pathway