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[DOI] [PMC free article] [PubMed] [Google Scholar] 60.Ewing GE

The sublingual epithelium simply cannot accommodate the passage of larger molecules through either paracellular or transcellular routes without assistance from permeation enhancers

966 As noted in the Mortality and Morbidity section, a person who lives from age 70 to age 80 with Alzheimer's dementia will spend an average of 40% of this time in the severe stage

When the brain can no longer compensate and cognitive problems interfere with a person's ability to perform everyday tasks such as driving, cooking or cleaning, a person is said to have dementia