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Release the solvent against the glass wall rather than directly onto the lyophilized powder

Author contributions SHN: Conceptualization, Data curation, Formal Analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Validation, Visualization, Writingoriginal draft

28 The cross-linkage and gellation of the solution form a matrix that is retained on the ocular surface by hydrophobic bonding to dry areas, as demonstrated by the reduction in corneal staining in clinical trials

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