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For example, in AD mouse models, inhibition or genetic ablation of the cyclophilin A (CypA)-MMP-9 pathway, which degrades EC tight junctions, has been shown to restore BBB integrity and slow down development of neurodegenerative changes in transgenic APOE4 mice

The compound is distinguished from BPC-157 by its systemic mechanism of action, while BPC-157 is thought to act locally at injury sites, TB-500 promotes cell migration and differentiation throughout the body by sequestering G-actin monomers and regulating cytoskeletal dynamics

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The guy looked at it and he goes, We can't even do anything with it