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Description

Equine SDFTs are commonly used as a functional equivalent to human Achilles tendon (Patterson-Kane and Rich, 2014) and they are the most commonly injured tendon in horses (Thorpe et al ., 2010a)

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Possible cause of immune side effects

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Lysyl oxidase, the copper-dependent enzyme that catalyzes the oxidative deamination of lysine residues in collagen and elastin (a step required for the cross-linking that gives mature collagen and elastin their mechanical properties), requires copper as a cofactor

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The cohort defines what the average can and cannot predict

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