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Genomics 23 (3), 226

Research has demonstrated that GHK-Cu treatment increases production of collagen (particularly type I and type III collagen, the predominant structural collagens in skin and connective tissues), glycosaminoglycans (including hyaluronic acid, which provides hydration, volume, and biochemical signaling in skin), decorin (a small proteoglycan involved in collagen fibril organization and growth factor regulation), and other matrix molecules critical for tissue structure and function

This is very important to think about, because eating different amounts of histamine from day to day can put women on a hormonal roller coaster of fluctuating estrogen levels