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failure of this regulation allows excessive IL-1 and IL-18 production, amplifying systemic inflammation, which is particularly relevant in SLE and RA

doi: 10.3389/fcell.2025.1556359 Received 06 January 2025 Accepted 12 March 2025 Published 26 March 2025 Volume 13 - 2025 Edited by Kihong Lim, University of Rochester, United States Reviewed by Florian Barthelemy, University of California, Los Angeles, United States Ha-Reum Lee, Chungnam National University, Republic of Korea Kanwal Ashiq, Superior University, Pakistan Updates Copyright 2025 Ye, Ren, Chen, Shen, Wang, Wu and Zhang

Yasuoka, S

Thats when supplementation becomes essential