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Antioxidant Defense GHK-Cu upregulates antioxidant enzymes including superoxide dismutase, catalase, and glutathione peroxidase, protecting cells against reactive oxygen species (ROS)-induced damage

Furthermore, secretion of 27HC by hepatocellular carcinoma cells enhances lipid metabolism in macrophages and activates peroxisome proliferator-activated receptor- (PPAR) signaling, driving M2-type macrophage polarization (39)

Materials and methods Clinical specimens The kidney samples were collected from the Renmin Hospital of Wuhan University

The antidepressant-like effects of melatonin in the forced swim test were hindered by luzindole, indicating that MT1 and MT2 receptors may be involved (Wang et al