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(PubMed) Kuriti M, Pearce EN, Braverman LE, He X, Leung AM

The direct antioxidant and free radical scavenging properties of melatonin are mainly due to its electron-rich aromatic indole ring, which makes it a potent electron donor that can significantly reduce oxidative stress 3,22

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In these conditions, the gut lining is compromised, allowing endotoxins and other antigens to leak into the bloodstream and trigger an immune response