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the loss of nigrostriatal dopaminergic neurons and the presence of intracellular cytoplasmic proteins, i.e., Lewy bodies, are also involved

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Constipation was assessed by frequency of defecation, response to laxatives and feces forms which were classified according to Bristol stool scale, (type 1 = separate hard lumps) (type 2 = sausage shaped and lumpy) (type3 = sausage shaped with cracks on its surface) (type 4 = sausage or snake with smooth surface) (type 5 = soft blobs) (type 6 = fluffy pieces) (type 7 = entirely liquid) 17