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The original version of this article was published on the Pulitzer Center website

Who It Is For Patients with stubborn visceral fat that resists diet and exercise Men and women experiencing metabolic slowdown associated with aging Patients with insulin resistance or metabolic syndrome who want to improve metabolic markers Anyone seeking meaningful body recomposition not just weight loss, but shifting the ratio of fat to lean mass Patients who have plateaued on a weight loss program and need a metabolic reset What to Expect Weeks 1-4: Improved energy and exercise tolerance as mitochondrial function improves

But as these medications became more common, another concern became more visible: some weight lost during treatment may come from lean mass, not just fat

Adults with severe deficiency usually get 1,000 mcg of vitamin B12