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Both the FDA and the Food and Agriculture Organization of the United Nations (FAO)/ World Health Organization (WHO) have concluded that the levels of glutamic acid and glutamate salts typically consumed pose no risk to public health or safety , and neither organization has set an upper limit for glutamate intake

These results confirm that tamoxifen induces oxidative damage in breast tumors in vivo and supports our hypothesis that ARE activation could contribute to the development of tamoxifen resistance