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Such self-diagnostic tools could reduce healthcare system burden and facilitate earlier detection with greater convenience

3A), among which 317, 567 and 631 DEGs were up-regulated, and 327, 504 and 367 DEGs were down-regulated (Fig

These limitations do not invalidate preclinical findings but emphasize the need for human clinical trials with appropriate sample sizes, standardized protocols, and validated outcome measures before establishing clinical efficacy in human patients

The maleimide group enters into all cells indiscriminately, which results in weaker cytotoxic effects, due to lacking of specific targeting