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Concerning the case of metastatic castration-resistant prostate cancer, a dose of cabazitaxel of 1025 mg/m 2 allowed the achieving of a median survival of 15.1 months ( 6 Pharmacokinetics, limitations, and strategies to increase the bioavailability and efficacy of taxanes 6.1 Pharmacokinetics of taxanes In humans, PTX exhibits pharmacokinetics that are non-linear

The next day, following three washes in TBST, the membranes were incubated with horseradish peroxidase (HRP)-conjugated anti-rabbit IgG (rabbit, A9169, 1:10,000, Sigma) or anti-mouse IgG (mouse, A9044, 1:10,000, Sigma) at room temperature for 1 h

By convention, the standard curve was constructed to describe the correlation between the fluorescence intensity of the solution containing DSNBD-GSH (10 M) at 478 nm and the concentration of GSH (02000 M)

Possibilities for diagnosis and regeneration of damaged intestinal barrier Evaluation of the level of intestinal barrier permeability is possible during indirect or direct diagnostic tests [124]