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For instance, the cyclin-dependent kinase inhibitor p21, which is a p53-regulated gene product with pro-survival properties, has been shown to associate with the DLG motif of Nrf2 (OReilly, 2005)

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The high specificity of these tests allows for a stacking approach whereby a subset of the 153 biomarker-based tests can be combined into a battery of tests that increases overall test sensitivity for a likelihood of autism