Most clinical trials to date have employed strains from the Lactobacillus and Bifidobacterium genera
Leukemia 15 , 16331640 (2001)
Melatonin restored the expression of genes involved in glycolysis (HK2, ENO1, PKM1, LDHA) and the TCA cycle (CS, IDH1, SUCLA2, FH, MDH1), reversed HO-induced metabolic disorders, increased the activity of mitochondrial oxidative phosphorylation complexes (II, III, and V), and increased the efficiency of ATP generation to safeguard the energy requirements of oocytes
Phytochemicals Many medicinal plants contain phytochemicals like phenolic and polyphenolic compounds such as flavonoids, isoflavones, flavones, anthocyanins, coumarins, lignans, catechin, isocatechin, gallic acid, and esculatin that possess antioxidant activities [77]