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Yet despite the lack of large-scale human research, pharmaceutical-grade BPC-157 is available to indicated users, and many people do opt to take advantage of its availability

In one sentence, the mechanism is receptor-mediated: GHRP binding to GHS-R1a activates a Gq/11-coupled phospholipase C cascade that mobilises intracellular calcium and triggers exocytosis of stored GH from the anterior pituitary, independent of hypothalamic GHRH signalling

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Medically Reviewed on 6/10/2026 Harvard T