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In addition to its role in neurotransmission, alpha-GPC exerts indirect antioxidant effects, contributing to the stabilization of neuronal membranes, improving synaptic function and optimizing mitochondrial metabolism, especially in conditions of oxidative stress and cognitive decline

To establish connection with the NO-system, L-NAME (5.0 mg/kg) (worsening) and L-arginine (200.0 mg/kg) (effective only with blunted NO-synthesis, but not alone) were given intraperitoneally alone or in combination (d-arginine 200.0 mg/kg was not effective, data not shown)

Early pernicious anemia symptoms are mild so mild that some people simply learn to live with feeling tired, lightheaded or breathless

When iron stores are sufficient, most intracellular Fe 2+ is sequestered in ferritin in an inactive form, while a small fraction forms the labile iron pool (LIP)