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The mechanism appeared to involve both direct endothelial repair and modulation of the fibrinolytic system

Astrotauopathies drive the pathophysiology of progressive supranuclear palsy, corticobasal degeneration, Picks disease, argyrophilic grain disease, globular glial tauopathies, and ageing-related tau astrogliopathy (ARTAG)

In many neurodegenerative diseases, the exact cause and pathology remains unknown, making it difficult to know whether the BBB dysfunction in the disease is a causative agent, a result of the disease, or somewhere in the middle

For instance, even something as subtle as the style of attention imparted by the dam to her offspring can induce pronounced epigenetic changes to GR expression