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Description

Reducing body fat , especially visceral adipose tissue, which drives aromatase activity and converts testosterone to estrogen

Six month old young rats were used as controls

The barrier failure comes first: When barrier proteins like filaggrin break down or are genetically underproduced, the skin loses its ability to retain moisture and block environmental triggers

Preclinical studies in rodent models have examined its interactions with nitric oxide signaling, angiogenic factors including VEGF, fibroblast migration, and collagen synthesis in various tissue types