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Neutrophil proteases promote experimental abdominal aortic aneurysm via extracellular trap release and plasmacytoid dendritic cell activation

A prominent example of OIS is the H-Ras G12V mutation, which triggers senescence by inducing the DDR mediated by ROS 17

So, DR may extend lifespan in part by preventing the aging-induced oxidation of these cytoplasmic redox ratios in C57BL/6N mice and by enhancing the aging-related reductive shifts in these cytoplasmic redox ratios in C57BL/6J mice

Similarly, after the death of cells that have experienced ferroptosis, intracellular components are also released in the form of DAMPs upon plasma membrane rupture, triggering the immune system to recruit neutrophils to the injured myocardium (Hu et al., 2021)