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The nasal formulation facilitates studies involving mucosal absorption and delivery mechanisms in vitro and ex vivo models

Although long used in biomedical applications, interest in biopolymers as antibacterial agents has surged, with publications on their use rising by approximately 400% since 2015 ( Approximately two decades ago, antibacterial biopolymers, e.g., those with intrinsic antibacterial activity, were first proposed as alternatives to antibiotics for treating bacterial infections ( Notably, NDBs disrupt bacterial membranes instead of targeting specific metabolic pathways, a mechanism less prone to resistance development ( 2 Antibiotics and antibiotic resistance In the pre-antibiotic era, more than half of deaths were attributable to infections (Table 1)

however, if bacteriostatic water is contaminated or not used correctly, it could contribute to injection site infections, swelling, or abscess formation

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