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DOI: 10.1016/j.abb.2008.11.017 6

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This acid is responsible for most vitamin B12 absorption from food during digestion, so the frequent use of antacids, PPIs, or H2-receptor inhibitors can lead to vitamin B12 deficiency

According to a 2017 systematic review in the Journal of Clinical Nursing confirming that aspiration before subcutaneous injection does not reduce adverse events, subcutaneous injections carry a distinct pharmacokinetic profile that intramuscular delivery disrupts, which is why correct angle and depth matter for predictable results