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Future Perspectives The scientific studies on seleno-GPxs have so far led to the understanding that the physiological role of seleno-GPxs is not only limited to detoxification of peroxides, but also involves regulating signaling pathways (such as chromatin remodulating, NF-B activation, insulin signaling, mitochondrial integrity, and ferroptosis, among others) [1, 8,9,10]

At the most basic level, glutathione cycles between a reduced form (GSH) and an oxidized form (GSSG)

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Adiponectin can inhibit the enhanced cytotoxic activity of natural killer (NK) cells that are induced by IL-2, as well as the production of IFN- (296)