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In the no-DAC form, that half-life is still short commonly reported on the order of roughly 30 minutes because there is no albumin-binding maleimide group to anchor the molecule in circulation
However, unbound, -LA and several of its metabolites are effective antioxidants
Thus, it is imperative that researchers, advocates, and policy makers continue to work together to identify evidence-based population-level interventions such as tobacco price increases, public health campaigns, age and marketing restrictions, cessation counseling and medications, and smoke-free laws to reduce smoking rates and smoking-related cancer burden in the United States
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