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Overall, authors suggest that oxidative stress along with purinoreceptor subtype 7/inflammasome pathway would play a persistent role in oxaliplatin-induced neurotoxicity and its transition from acute to chronic NP

In the studies discussed below it is an umbrella term for several distinct, separately measurable events: Neurogenesis the birth of new neurons from neural progenitor cells, typically assessed with markers such as BrdU incorporation and doublecortin