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We suggest starting doses using PCCA Naltrexone Hydrochloride USP Anhydrous (PCCA # 50-4377 ), prepared in 0.5 mg capsules with LoxOral (PCCA # 30-4774 ) as the filler, and titrate 0.5 mg every two weeks up to a maximum of 4.5 mg daily

Therefore, its important to maintain the balance between Glutamate and other neurotransmitters, such as GABA (gamma-aminobutyric acid), which is an inhibitory neurotransmitter that counters the excitatory effects of Glutamate

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This loss of neurons and diminished synaptic connectivity is particularly apparent in the hippocampus (Gao et al., 2011