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The number of mitochondria in a cell can vary widely [2]

By attaching an acetyl group to the sulfur atom of cysteine within the glutathione tripeptide, SAG resists enzymatic degradation in the gastrointestinal tract, crosses cell membranes intact, and is then hydrolyzed intracellularly by cytoplasmic thioesterases to release free, bioactive GSH directly inside cells

In particular, GSH is involved in nutrient metabolism, antioxidant defense, and regulation of cellular metabolic functions ranging from gene expression, DNA and protein synthesis to signal transduction, cell proliferation and apoptosis

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